diff --git a/scene/gui/control.cpp b/scene/gui/control.cpp
index 8cf5c3f2937..ecfdb28d963 100644
--- a/scene/gui/control.cpp
+++ b/scene/gui/control.cpp
@@ -2349,6 +2349,13 @@ void Control::grab_focus(bool p_hide_focus) {
 	ERR_MAIN_THREAD_GUARD;
 	ERR_FAIL_COND(!is_inside_tree());
 
+	if (get_focus_mode_with_override() == FOCUS_ACCESSIBILITY) {
+		if (!get_tree()->is_accessibility_enabled()) {
+			WARN_PRINT("This control can grab focus only when screen reader is active. Use set_focus_mode() and set_focus_behavior_recursive() to allow a control to get focus. Use get_tree().is_accessibility_enabled() to check screen-reader state.");
+			return;
+		}
+	}
+
 	if (get_focus_mode_with_override() == FOCUS_NONE) {
 		WARN_PRINT("This control can't grab focus. Use set_focus_mode() and set_focus_behavior_recursive() to allow a control to get focus.");
 		return;